Shop RxOneShop's Best Selling Pharmaceuticals

Brand Name, Generic, CBD, Diabetic, Short Dated Supplies & More!

Looking for brand name pharmaceuticals and generic pharmaceuticals online? RxOneShop is a leading pharmaceutical distributor in the United States, serving our customers since 2005. We are a trusted pharmaceutical distributor, with years of industry experience perfecting our online experience to make it easy to find best-selling medications and pharmaceutical supplies!

At RxOneShop, we continue to offer the most competitive pricing and provide the lowest prices available to pharmacies on best-selling generic and brand name prescription drugs, bulk over the counter medications, injectables, vitamins, CBD wholesale products, and medical supplies alike.

In addition, our partnerships with a variety of pharmaceutical suppliers give us access to the best wholesale costs on the most popular medications, including Generic ABILIFY® (aripiprazole), Clobetasol, Omeprazole, generic Synthroid (levothyroxine), and Lidocaine.

1. NSAIDS (Nonsteroidal anti-inflammatory drugs)


Browse all best-selling NSAIDs with RxOneShop online! Nonsteroidal anti-inflammatory drugs, commonly known as NSAIDs, encompass a wide range of medications including ibuprofen, naproxen, and aspirin, among others. These drugs are primarily used for their anti-inflammatory, analgesic (pain-relieving), and antipyretic (fever-reducing) properties.

NSAIDs operate by inhibiting the body's production of certain substances that cause inflammation, pain, and fever, making them a versatile choice for treating conditions such as arthritis, menstrual pain, headaches, and muscle aches.

While highly effective, it is important for users to be aware of the potential side effects associated with long-term or excessive use of NSAIDs, such as increased risk of gastrointestinal bleeding, ulcers, and kidney damage.

As such, it's important to adhere to recommended dosages and consult healthcare professionals for appropriate use, especially for individuals with existing health conditions or those taking other medications.

2. Antihistamines


Another type of best selling OTC drug are antihistamines, which are a class of medications designed to counteract the effects of histamine, a substance in the body that triggers allergy symptoms like sneezing, itching, runny nose, and watery eyes.

Common antihistamines include Diphenhydramine  (Benadryl), Loratadine, Cetirizine (Zyrtec), Fexofenadine (Allegra), Ketotifen (found in Zaditor and Alaway), Olopatadine (Pataday), and Azelastine (Astepro).

These medications are available in various forms, such as capsules, tablets, liquids, eye drops, and nasal sprays, offering flexible options for addressing different allergy symptoms and severity levels. Antihistamines work by blocking the action of histamine, providing relief from the discomfort associated with allergic reactions.

3. Generic ABILIFY® (aripiprazole)


One of our best selling pharmaceutical products is Generic ABILIFY® (aripiprazole).

Order your supply of Generic ABILIFY® (aripiprazole) from RxOneShop. Through our partnerships with our suppliers, we can offer this widely-used medication to your retail, chain, or specialty pharmacy at a low cost.

Doctors across the United States frequently prescribe this drug. So we understand how important it is to keep Aripiprazole in stock! You can count on our pharmaceutical company to supply you with the quantities of Generic ABILIFY® that you need on-demand.

You can either order Generic ABILIFY® and other best selling pharmaceuticals online or (877) 476-4761.

4. Clobetasol Ointments, Creams, & Sprays


Another one of our best selling pharmaceutical products are our Clobetasol ointments, cream, sprays, and other products.

If you manage a long-term care facility, chain store, retail store, or specialty pharmacy, choose RxOneShop as your Clobetasol supplier! Our pharmaceutical company provides both generic and brand name Clobetasol propionate in a variety of topical forms, including emollients, creams, ointments, gel, sprays, and foam, to meet your customers’ needs.

For over a decade, we have worked with leading pharmaceutical suppliers to provide pharmacies with unbeatable wholesale prices on prescription medications. Order generic Clobetasol or brand name Temovate from RxOneShop, and receive the best discounts on the market with next-day shipping options.

Contact RxOneShop today with questions about our Clobetasol pharmaceuticals, or order online or over the phone.

5. Omeprazole


Omeprazole is easily one of the most popular prescription and over the counter medications. Omeprazole is a widely used medication, available both by prescription and over-the-counter, that belongs to a class of drugs known as proton pump inhibitors (PPIs).

It is designed to reduce the amount of acid produced in the stomach, making it an effective treatment for conditions such as gastroesophageal reflux disease (GERD), stomach ulcers, and Zollinger-Ellison syndrome. By decreasing stomach acid, omeprazole can help alleviate symptoms like heartburn, difficulty swallowing, and persistent cough, promoting healing of the esophagus and stomach lining.

RxOneShop offers prescription-strength generic Omeprazole to certified, licensed pharmacies at the lowest market prices available. We also sell bulk supplies of over the counter Omeprazole. All Omeprazole products can be shipped to your pharmacy within 24 hours.

6. Generic Synthroid (Levothyroxine)


One of the most in-demand and best selling pharmaceuticals is Levothyroxine, or generic Synthroid. This best-selling OTC drug is a synthetic thyroid hormone replacement medication primarily used to treat hypothyroidism—a condition where the thyroid gland does not produce enough thyroid hormone.

It regulates the body's energy and metabolism, and by supplementing or replacing the natural thyroid hormone, Levothyroxine helps restore normal bodily functions. It may also be prescribed for other thyroid-related conditions, such as certain types of goiters.

RxOneShop provides pharmacies with the cheapest prices available on generic Synthroid (Levothyroxine). We offer next-day delivery on this popularly prescribed thyroid medication. As with all of the pharmaceuticals that we distribute, we guarantee that your pharmacy will obtain Levothyroxine at the best wholesale cost possible. Browse RxOneShop online for generic Synthroid (Levothyroxine) pharmaceuticals!

7. Lidocaine


RxOneShop can provide your pharmacy with both prescription strength and OTC (over the counter) Lidocaine. Lidocaine is a versatile medication widely recognized for its local anesthetic and antiarrhythmic properties. It works by blocking nerve signals in the body, making it an essential choice for providing local anesthesia during surgical procedures, dental work, and for relieving minor burns, injuries, and certain skin conditions. Additionally, Lidocaine is used in managing heart rhythm disorders due to its ability to stabilize the cardiac membrane.

Our pharmaceutical company offers oral and topical Lidocaine cream, gel, liquid, and ointment, as well as aerosol sprays and topical patches. We also supply infusion pharmacies and long-term care facilities with injectable doses of Lidocaine. Whether you need a bulk stock of this popular local anesthetic or small quantities, RxOneShop can help!

We offer low-cost solutions and a variety of shipping options to meet your pharmacy’s needs. Browse RxOneShop online for discount prices on Lidocaine gels, sprays, liquids, and ointments alike.

8. Beano (Alpha-Galactosidase)


Another best-selling pharmaceutical medication people take is Beano/Alpha-Galactosidase. For individuals experiencing digestive discomfort due to consumption of foods rich in complex carbohydrates, such as beans and cruciferous vegetables like broccoli, Beano might offer a preventative solution.

The primary active enzyme in Beano is alpha-galactosidase. This enzyme specifically targets and breaks down oligosaccharides, the sugars found in these difficult-to-digest foods, potentially reducing the incidence of gas and bloating.

By acting before the consumption of gas-producing foods, Beano can facilitate the digestion of these sugars, thereby possibly mitigating digestive discomfort.

9. Pepto-Bismol (Bismuth Subsalicylate)


Pepto-Bismol, scientifically known as bismuth subsalicylate, serves as a multi-purpose over-the-counter medication aimed at alleviating various digestive system complaints. It is notably effective in addressing symptoms such as nausea, heartburn, indigestion, upset stomach, and diarrhea.

The compound works by providing a protective coating to the stomach lining, thereby reducing inflammation and irritation. Additionally, it possesses antimicrobial properties that can combat certain bacteria, including those responsible for causing stomach ulcers. Unlike some digestive aids that target specific enzymes or gases, Pepto-Bismol offers a broader spectrum of relief for common gastrointestinal disturbances.

It's important for users to follow dosage instructions and be aware of potential side effects, such as temporary blackening of the tongue and stools, which are harmless but may be surprising.

Save Money On Our Best Selling Pharmaceuticals!


We help you save money! If you own or manage a certified, licensed pharmacy, it's easy to open a free account with RxOneShop today. We guarantee low prices, next-day shipping options, and flexible payment terms.

We offer these and other top pharmaceuticals at the lowest wholesale prices available! We work with VAWD pharmaceutical suppliers, and we distribute medications to retail, chain, combo, fusion, long-term care, and specialty pharmacies.

Contact RxOneShop for Best-Selling Pharmaceuticals & Medications!


Need help on how to find pharmacy products on our website? Check out our article here.

Start saving today – call RxOneShop or complete our simple online application and get the best prices on leading drugs and medical supplies. We are an experienced wholesale drug supplier, serving our clients for many years.

Ready to get started with our pharmacy wholesaler? Give our team a call today, or browse our brand name, generic, short-dated, hard-to-find, diabetic, pharmaceuticals online today. For a complete list of best selling pharmaceutical drugs, please take a look at our prescription drug resource list.

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