Over-The-Counter (OTC) drugs are medications that are readily available at pharmacies and do not require a prescription from a healthcare provider.

While they are generally considered safe for public consumption, understanding OTC drug brands can help consumers make more informed decisions regarding their health.

What Are OTC Drugs?

An Over-The-Counter (OTC) drug is a medication that is sold directly to consumers without a prescription from a healthcare provider.

These drugs are available for a wide range of conditions, from minor aches and pains to cold and flu symptoms, skin conditions, and digestive issues and have been tested thoroughly to ensure their safety, efficacy, and quality. Here is a long list of OTC drug brands that you should know.

The Importance of Brands in OTC Drugs

Brands serve several functions in the OTC drug market:

  • Quality Assurance: Established brands often invest in research and quality control, ensuring that their products meet high standards.
  • Consumer Trust: Brand recognition builds trust. If a consumer has had a positive experience with a particular brand, they are more likely to purchase from it again.
  • Information: Packaging and branding often provide important information, including active and inactive ingredients, dosages, and warnings.
  • Specialization: Some brands focus on specific types of medication, such as cold and flu remedies or digestive aids, becoming specialists in those areas.

Popular OTC Drug Brands


Tylenol is a trusted over-the-counter medication brand owned by Johnson & Johnson. The primary active ingredient in Tylenol products is acetaminophen, which serves as an effective analgesic (pain reliever) and antipyretic (fever reducer).

We typically recommend using Tylenol for helping to relieve conditions such as headaches, arthritis, and post-surgical pain. It is available in various forms including tablets, caplets, liquid, and even intravenous solutions. Here is more information about how to use Tylenol.


Advil is a brand of over-the-counter medication owned by Pfizer, and its main active ingredient is ibuprofen. Classified as a Nonsteroidal Anti-Inflammatory Drug, Advil is frequently used to relieve pain, reduce inflammation, and lower fever. Advil is commonly available in tablets, liquid capsules, and topical solutions on our website.

Advil is considered versatile, as it is effective for treating everything from toothaches and menstrual cramps to more severe conditions like rheumatoid arthritis. If you have questions about proper use of Advil, please don't hesitate to contact our team today.


Tums is a widely recognized brand of antacid that is owned by the pharmaceutical giant GlaxoSmithKline. Utilizing calcium carbonate as its primary active ingredient, Tums is formulated to neutralize stomach acid and provide quick relief from heartburn, acid indigestion, and sour stomach.

Tums tablets, available on the RxOneShop website, are often flavored and chewable, making them easy to take for quick relief. 


Owned by Procter & Gamble, Pepto-Bismol is a go-to medication for various gastrointestinal issues. The product contains bismuth subsalicylate as its active ingredient and is aimed at providing symptomatic relief from stomach upset, indigestion, heartburn, and diarrhea.

Available in multiple forms, including liquid, chewable tablets, and caplets, Pepto-Bismol offers a comprehensive approach to tackling a range of stomach ailments.


If you're struggling with allergies, we highly recommend looking into Benadryl, another brand under Johnson & Johnson. Benadryl is an antihistamine medication widely used for treating symptoms of allergies and colds such as sneezing, itching, and a runny nose.

One thing to note for Benadryl users: the primary active ingredient is diphenhydramine, which is effective but can also be sedating. This makes Benadryl a less ideal option for situations that require high levels of alertness.


Also owned by Johnson & Johnson, Zyrtec is an antihistamine that is usually less sedating compared to Benadryl. It contains cetirizine as its active ingredient.

Zyrtec can provide 24-hour relief, and it's effective for using to treat symptoms like itching, sneezing, and hives. As such, Zyrtec is considered to be a good option for long-term management of allergy symptoms.


Claritin is an antihistamine medication brand owned by Bayer. Containing loratadine as its active ingredient, Claritin is engineered to provide relief from allergy symptoms without causing drowsiness, thus giving it an edge over more sedating options like Benadryl.

Claritin is available in several forms on our website. You can find the product in tablet dissolvable strips, and liquid form.


Owned by Procter & Gamble, NyQuil and DayQuil helps to relieve and treat cold and flu symptoms. NyQuil is designed for nighttime use and often includes antihistamines to aid sleep, while DayQuil is formulated for daytime use and avoids ingredients that cause drowsiness.

Both include a combination of active ingredients like acetaminophen for pain relief and fever reduction, along with decongestants and cough suppressants.

Factors to Consider When Choosing an OTC Drug Brand

When choosing your OTC drug brand, you should take into account the active ingredient, its recommended dosage, the potential side effects you may experience, and the overall price and whether the cost makes sense for you:

  • Active Ingredient: Always look for the active ingredient and make sure it suits your needs.
  • Dosage: Ensure the dosage matches the recommendation of a healthcare provider or follows the guidelines on the packaging.
  • Side Effects: Read the label for possible side effects and interactions with other medications or conditions.
  • Price: While brand-name drugs are generally more expensive, generic versions usually contain the same active ingredients and are often just as effective.

Understanding OTC drug brands can help consumers make better choices when it comes to self-medication. Brands offer quality assurance, consumer trust, and specialized products.

As always, you need to read labels carefully and consult with our healthcare providers if you have concerns or questions. Contact us here today.

Why Choose RxOneShop?

RxOneShop has nearly two decades of industry experience. We are a reliable pharmaceutical company that holds ourselves to the highest standards, so you can trust us to be a reliable source of OTC drugs, supplies, and more!

Contact our OTC drug distributors today, or contact us at (877) 476-4761 for more information!